BI196: Turmeric-Longan Seed Acne Film

Viwat Sutana Vareechiangmai School

MIIX24 | Beginner Innovator

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Acne is a common skin condition that can occur at any age, but is most prevalent during adolescence to adulthood. The problem of acne significantly impacts the confidence of many individuals, affecting various aspects of life including quality of life, mental well-being, and social interactions. One of the problematic manifestations of acne is inflammatory acne, characterized by red, swollen bumps or sometimes pustules at the site of the acne lesion, which can be visibly prominent. There are various ways to address acne, including topical or oral medications. However, some acne treatments may lead to side effects such as skin irritation, dryness, peeling, itching, or redness. Even when acne clears, issues like red or dark spots resulting from acne scars can persist, which are often challenging to treat. Research has shown that lychee seed contains polyphenols that can help reduce inflammation, while turmeric can inhibit the growth of the bacteria involved in acne formation. Researchers have developed an acne-covering film incorporating lychee seed and turmeric extracts. In a study, after measuring the clear zone diameter from agar plates inoculated with acne-causing bacteria, it was found that turmeric extracts at concentrations of 100, 50, 25, and 12.5 percent (w/v) showed average clear zone diameters of 8.63, 8.43, 8.65, and 7.7 mm, respectively, against oxygen-utilizing bacteria. For non-oxygen utilizing bacteria, the average clear zone diameters were 9.08, 8.71, 8.96, and 11.28 mm, respectively. When compared to common antibiotics like Vancomycin, the average clear zone diameters for oxygen-utilizing and non-oxygen utilizing bacteria were 31.6 and 37.13 mm, respectively. For Azithromycin, the average clear zone diameters were 10.92 and 16.9 mm, respectively, and for Roxithromycin, they were 35.13 and 45.95 mm, respectively. The results indicate that turmeric extracts can inhibit acne-causing bacteria, but their efficacy may not be equivalent to commonly used